COVID19 Disease Map Project logo COVID-19 Disease Map

We aim to establish a knowledge repository of molecular mechanisms of COVID-19 as a broad community-driven effort.
Here we share resources and best practices to develop a COVID-19 Disease Map of these mechanisms.
The COVID-19 Disease Map is an assembly of molecular interaction diagrams, established based on literature evidence.
We focus on host-pathogen interactions specific to the SARS-CoV-2 virus.

FAIRDOMHub project space lists our contributors, data and computational models, and literature.

Publication

COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms. Ostaszewski M, Mazein A, Gillespie ME, Kuperstein I, Niarakis A, Hermjakob H, Pico AR, Willighagen EL, Evelo CT, Hasenauer J, Schreiber F, Dräger A, Demir E, Wolkenhauer O, Furlong LI, Barillot E, Dopazo J, Orta-Resendiz A, Messina F, Valencia A, Funahashi A, Kitano H, Auffray C, Balling R, Schneider R. Sci Data. 2020 May 5;7(1):136. doi: 10.1038/s41597-020-0477-8. PubMed PMID: 32371892.

Contributors

Please use this Google Sheet form to let us know how would you like to contribute to the development of the map.

Subscribe to our mailing list for updates and discussions.

We have Slack channels for curation of the diagrams and for modelling.
To join these Slack channels, contact marek.ostaszewski(at)uni.lu.

More details about the project can be found in our ‘welcome pack’.

Curation

We share interesting COVID-19 articles using a Zotero group. The group is public-by-invitation to allow file sharing.

Check curation guidelines to harmonize your content for easier sharing and integration. The guidelines contain information about regular TCs where we discuss our progress.

Content repositories

Curated diagrams and code are shared using our public Gitlab repository.
Access with your GitHub login and request developer privileges, or contact marek.ostaszewski(at)uni.lu.

WikiPathways can be shared using a dedicated collection with COVID-19 related pathways.

A weekly build is available on the MINERVA Platform.

Useful resources

Relevant databases, literature and datasets can be found on the resources page.

Curation resources:

Modelling efforts: