COVID19 Disease Map Project logo COVID-19 Disease Map

We aim to establish a knowledge repository of molecular mechanisms of COVID-19 as a broad community-driven effort.
Here we share resources and best practices to develop a COVID-19 Disease Map of these mechanisms.
The COVID-19 Disease Map is an assembly of molecular interaction diagrams, established based on literature evidence.
We focus on host-pathogen interactions specific to the SARS-CoV-2 virus.

FAIRDOMHub project space lists our contributors, data and computational models, and literature.

COVID-19 Disease Map table of contents lists the available diagrams, togehter with access details and browsing instructions.

Our publications

COVID-19 Disease Map, a computational repository of SARS-CoV-2 virus-host interaction mechanisms.
Mol Syst Biol. 2021 Oct;17(10):e10387. doi: 10.15252/msb.202110387. doi: 10.15252/msb.202110387. PubMed PMID: 34664389.

COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms.
Sci Data. 2020 May 5;7(1):136. doi: 10.1038/s41597-020-0477-8. PubMed PMID: 32371892.


Join the project via the FAIRDOMHub project space.

Subscribe to our mailing list for updates and discussions.

We have Slack channels for curation of the diagrams and for modelling.
To join these Slack channels, contact marek.ostaszewski(at)

More details about the project can be found in our ‘welcome pack’.


We share interesting COVID-19 articles using a Zotero group. The group is public-by-invitation to allow file sharing.

Check curation guidelines to harmonize your content for easier sharing and integration. The guidelines contain information about regular TCs where we discuss our progress.

Content repositories

Curated diagrams and code are shared using our public Gitlab repository.
Access with your GitHub login and request developer privileges, or contact marek.ostaszewski(at)

WikiPathways can be shared using a dedicated collection with COVID-19 related pathways.

Reactome releases SARS-CoV infections diagrams with mechanisms relevant for COVID-19.

A weekly build is available on the MINERVA Platform.

Useful resources

Curation resources:

Modelling efforts:

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